Racecadotril Véase también Referencias Menú de navegaciónPMID 10804038Free full text with...


Antidiarreicos


antidiarreicoencefalinasaelectrólitosrehidratación oral






Racecadotril


Racecadotril es un agente antidiarreico que actúa como un inhibidor periférico de encefalinasa.[1]​ A diferencia de otros medicamentos usados para tratar la diarrea, que disminuyen la motilidad intestinal, racecadotril[2]​ tiene un efecto antisecretorio, reduciendo la secreción de agua y electrólitos al intestino.[3]​


Una prueba aleatorizada controlada halló que racecadotril reducía estadística significantivamente la duración y el volumen de diarrea acuosa en niños cuando se administraba concomitantemente con rehidratación oral.[4]​



Véase también


  • Encefalina


Referencias




  1. ↑ Matheson AJ, Noble S. Racecadotril. Drugs. 2000 Apr;59(4):829-35. PMID 10804038


  2. ↑ http://www3.interscience.wiley.com/cgi-bin/fulltext/120122537/PDFSTART antisecretory infectious diarrhoea in children: new insights in antisecretory treatment with racecadotril Acta Paediatrica


  3. ↑ (2001) "Racecadotril: an Antidiarrhoeal Suitable for Use in Infants and Young Children". Drug Ther Perspect 17 (8): 1–5. Free full text with registration at Medscape


  4. ↑ Salazar-Lindo E, Santisteban-Ponce J, Chea-Woo E, Gutiérrez M (2000). «Racecadotril in the treatment of acute watery diarrhea in children». N. Engl. J. Med. 343 (7): 463-7. PMID 10944563. doi:10.1056/NEJM200008173430703. 








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